Impairment of Myocardial 02 Supply due to Hyperventilation
نویسندگان
چکیده
Thirteen patients with ischemic coronary heart disease purposely hyperventilated for seven minutes in order to induce hypocapnic alkalosis. One patient experienced chest pain, and one exhibited chemical signs of myocardial hypoxia. Heart rate, blood pressure and myocardial 02 consumption did not change significantly. Coronary blood flow decreased and coronary (a-v)O2 difference widened. Since the alkalosis increased the blood 02 affinity, the fall in Po2 in coronary venous blood was proportionately even greater than the fall in 02 concentration. Thus, hypocapnic alkalosis due to hyperventilation interferes with myocardial
منابع مشابه
Impairment of myocardial O2 supply due to hyperventilation.
Thirteen patients with ischemic coronary heart disease purposely hyperventilated for seven minutes in order to induce hypocapnic alkalosis. One patient experienced chest pain, and one exhibited chemical signs of myocardial hypoxia. Heart rate, blood pressure and myocardial O2 consumption did not change significantly. Coronary blood flow decreased and coronary (a-v)O2 difference widened. Since t...
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